VIAGRA contains sildenafil, which is similar medicine found in An additional drug identified as REVATIO. REVATIO is applied to take care of a uncommon disorder identified as pulmonary arterial hypertension (PAH).
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Scientific data have revealed that co-administration with saquinavir or erythromycin enhanced plasma levels of sildenafil by about 3 fold [see DRUG INTERACTIONS and CLINICAL PHARMACOLOGY].
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The use of VIAGRA delivers no security in opposition to sexually transmitted diseases. Counseling of clients about the protecting measures needed to guard against sexually transmitted health conditions, such as the Human Immunodeficiency Virus (HIV), could possibly be thought of.
i.d.) resulted in a very sixty three% reduce of sildenafil AUC and a fifty five% minimize in sildenafil Cmax . Concomitant administration of robust CYP3A4 inducers, including rifampin, is expected to lead to greater decreases in plasma levels of sildenafil.
VIAGRA may influence the way in which other medicines function, as well as other medicines could affect the best way VIAGRA is effective producing Unwanted side effects. In particular explain to your Health care provider if you take any of the subsequent:
Results of Other Medicine on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (important route) and CYP2C9 (small route). Thus, inhibitors of these isoenzymes may decrease sildenafil clearance and inducers of these isoenzymes sikik may possibly raise sildenafil clearance.
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